The US-born giant panda Bei Bei has left his home at Washington's National Zoo for China.
Bei Bei will travel on a specially equipped flight from Washington to Chengdu, accompanied by his keeper and a veterinarian.
The giant panda turned four years - the age when all pandas born outside return to China under their breeding agreements.
"Today is bittersweet. We've cared for Bei Bei, and along with millions, watched him grow into a true ambassador for his species," said zoo director Steve Monfort.
"We look forward to continuing our 47-year giant panda conservation program and collaboration with Chinese colleagues to study, care for and help save the giant panda and its native habitat."
Zoo officials said they had prepared a special stash of treats for him: 30 kilos of bamboo, two pounds of apples and pears, two pounds of cooked sweet potatoes, two bags of biscuits and water.
An explosive-laden car rammed into a Pakistani military convoy on Saturday in a town near the Afghan border, killing at least 13 soldiers, sources said.
Radiation levels in the Gulf region remain normal after the 12-day Israel-Iran conflict severely damaged several nuclear facilities in Iran, Director General Rafael Mariano Grossi of the International Atomic Energy Agency (IAEA) said.
Rwanda and Democratic Republic of Congo signed a US-brokered peace agreement on Friday, raising hopes for an end to fighting that has killed thousands and displaced hundreds of thousands more this year.
The US Supreme Court on the last day of rulings for its current term gave Donald Trump his latest in a series of victories at the nation's top judicial body, one that may make it easier for him to implement contentious elements of his sweeping agenda as he tests the limits of presidential power.
Polish President Andrzej Duda arrived in Kyiv on Saturday for a meeting with Ukrainian President Volodymyr Zelenskyy, Duda's office said, as Kyiv aims to build support among allies at a critical juncture in its grinding war with Russia.