England bowled West Indies out for 45 - the second lowest total in international Twenty20 history - to win by 137 runs in St Kitts.
Joe Root's 55 runs and Sam Billings' brilliant knock of 87 off 47 balls helped to win with ease, taking an unassailable 2-0 lead in the series.
This is England's biggest margin of victory by runs in T20s and the fourth biggest of all time.
The final T20 will be played in St Kitts at 20:00 GMT on Sunday.
Sunderland's Xhaka earns draw after Ndiaye's stunner for Everton
Iliman Ndiaye scored a superb solo goal for Everton but Granit Xhaka's deflected equaliser secured a deserved point for Sunderland in their entertaining 1-1 Premier League draw at the Stadium of Light on Monday.
Rybakina enters semis, Anisimova beats Keys in WTA Finals
Elena Rybakina qualified for the WTA Finals' last four, beating an error-prone Iga Swiatek 3-6 6-1 6-0 on Monday, while Amanda Anisimova beat fellow American Madison Keys 4-6 6-3 6-2 in Riyadh.
DP World Tour Championship gears up for action-packed week
With just 10 days until the season-ending showdown at Jumeirah Golf Estates, the DP World Tour Championship, Dubai is set to deliver an unforgettable experience both on and off the course as the world's best golfers battle for glory from November 13-16.
India win maiden Women's World Cup title after Verma-Sharma show
India's agonising wait for a maiden Women's World Cup title finally came to an end as Harmanpreet Kaur and her teary-eyed teammates clinched the trophy by beating South Africa in a dramatic final at the DY Patil Stadium on Sunday.
World's oldest living gold medallist Charles Coste dies at 101
French cyclist Charles Coste, who had been the world’s oldest living Olympic gold medallist, has died aged 101, French media reported on Sunday.
