World number one Aryna Sabalenka's quest for her first Wimbledon title will begin against Canadian qualifier Carson Branstine while second seed Coco Gauff's opener will be versus Ukraine's Dayana Yastremska.
Friday's draw also pitched defending champion Barbora Krejcikova, the 17th seed, against Alexandra Eala of the Philippines.
Third seed Jessica Pegula's first-round opponent is Italian qualifier Elisabetta Cocciaretto, while fourth seed Jasmine Paolini, runner-up last year, faces Anastasija Sevastova of Latvia.
Belarusian Sabalenka could meet Paolini in the semi-finals while Gauff is in line for a clash with fellow American Pegula.
British number one Emma Raducanu faces an intriguing opening round match against compatriot Mingge Xu, one of three British teenaged wildcards in the draw.

Magnitude wins $12million Dubai World Cup
Sabalenka beats Gauff in Miami final, completes 'Sunshine Double'
Eight players leave England camp ahead of Japan friendly
American Malinin earns Olympic redemption with world gold
Kohli and Duffy star as defending champions RCB overpower Hyderabad
