Serena Williams will play Maria Sharapova in the first round of the US Open at Flushing Meadows in New York.
The sporting giants haven't contested a match since the Australian Open quarter-final of 2016.
In fact, they were supposed to meet at the French Open last year but Williams pulled out citing a pectoral injury.
Meanwhile, Naomi Osaka will play Anna Blinkova of Russia, while Britain's Johanna Konta faces Daria Kasatkina of Russia.
Elsewhere in the men's draw, Spain's Rafael Nadal will play Australian John Millman while Novak Djokovic begins his title defence against Spaniard Roberto Carballes Baena.
Roger Federer is set to face a qualifier.

Arsenal beat Man City 3-0 to win Community Shield
Cristiano Ronaldo hints at retirement amid 'last year' claims
Sri Lanka fight back through spinners but India 460-9
Man arrested on suspicion of fraud after security operation disrupts European Championships
Bangladesh claim first test win in Australia as Green ton in vain
