England beat Ireland and France by 12 and 36 points respectively in their first two matches of the campaign.
They are currently ranked third in the world.
Play from the Millennium Stadium in Cardiff gets underway at 8:45 PM UAE time.
Meanwhile Scotland travel to France for their latest Six Nations fixture.
Action from the Stade de France starts at 6:15 PM UAE time.
Liverpool's Salah to end glittering Anfield career at end of season
Mohamed Salah, one of Liverpool's greatest-ever players and the driving force behind the club's modern era of success, will leave Anfield at the end of the season.
European fans file complaint over World Cup ticket prices
European football fans have lodged a formal complaint over the high cost of tickets for this summer's FIFA World Cup in North America.
Wood claims MENA Golf Tour rankings title after regional tensions end season
Englishman Chris Wood has claimed the 2025/26 MENA Golf Tour rankings title following the conclusion of the Morocco Series with regional tensions bringing an end to the season.
Klopp shuts down Real Madrid speculation, still open to coaching return
Former Liverpool manager Juergen Klopp has dismissed speculation linking him with the Real Madrid job, though the German said he was not completely finished as a coach.
AFC confirm Jeddah to host postponed Asian Champions League matches
Four Asian Champions League Elite ties that were postponed due to the conflict in the Middle East will be moved to Jeddah and played on a single-leg basis next month, the Asian Football Confederation said on Tuesday.
