Jason Roy and captain Joe Root both smashed centuries as the tourists easily reached their target of 361 with eight balls to spare in Barbados.
It was their highest ever run-chase in the format.
Chris Gayle's innings of 139 off 129 balls went in vain as the Windies' poor form in ODI cricket continued.
The second encounter of the five-match series will be played on Friday.
Mac Allister heads Liverpool to Champions League win over Real Madrid
Liverpool's Alexis Mac Allister headed a second-half winner as the hosts earned a hard-fought 1-0 victory over Real Madrid in a battle between European giants on Tuesday, handing the LaLiga leaders their first defeat in the Champions League this season.
Sabalenka overpowers Pegula, Gauff eliminates Paolini in WTA Finals
World number one Aryna Sabalenka earned a 6-4 2-6 6-3 win over Jessica Pegula, while defending champion Coco Gauff put on a clinical performance to beat Jasmine Paolini 6-3 6-2 and eliminate the Italian in Riyadh on Tuesday.
Pakistan win ODI against South Africa in last over as Salman shows the way
Salman Ali Agha top scored for Pakistan as they snatched a last-over victory over South Africa on Tuesday in an exciting finish to the first of three One Day Internationals at Faisalabad.
David Beckham knighted for services to sport and charity
David Beckham, one of Britain's most celebrated football players, was knighted by King Charles at Windsor Castle on Tuesday, recognising his decades-long contribution to sport and charitable causes.
Aryna Sabalenka challenges Nick Kyrgios in Dubai showdown
Tennis fans are in for a treat this December as WTA World No. 1 Aryna Sabalenka takes on showman Nick Kyrgios in a one-off exhibition match, Battle of the Sexes: The Dubai Showdown.
