Jason Roy and captain Joe Root both smashed centuries as the tourists easily reached their target of 361 with eight balls to spare in Barbados.
It was their highest ever run-chase in the format.
Chris Gayle's innings of 139 off 129 balls went in vain as the Windies' poor form in ODI cricket continued.
The second encounter of the five-match series will be played on Friday.
Wood claims MENA Golf Tour rankings title after regional tensions end season
Englishman Chris Wood has claimed the 2025/26 MENA Golf Tour rankings title following the conclusion of the Morocco Series with regional tensions bringing an end to the season.
Klopp shuts down Real Madrid speculation, still open to coaching return
Former Liverpool manager Juergen Klopp has dismissed speculation linking him with the Real Madrid job, though the German said he was not completely finished as a coach.
AFC confirm Jeddah to host postponed Asian Champions League matches
Four Asian Champions League Elite ties that were postponed due to the conflict in the Middle East will be moved to Jeddah and played on a single-leg basis next month, the Asian Football Confederation said on Tuesday.
Madrid's Mbappe fit and ready to play every game before World Cup
France striker Kylian Mbappe has stated he has fully recovered from a knee injury and wants to play all of Real Madrid's remaining matches in the season run-in as he builds toward the World Cup.
Cerundolo's Miami magic continues with stunning Medvedev upset
Francisco Cerundolo's love affair with the Miami Open shows no signs of cooling after the Argentine world number 19 stunned Russian Daniil Medvedev 6-0 4-6 7-5 to reach the fourth round on Monday.
