Arsenal and Chelsea made it through to the Europa League last-eight while Inter and Sevilla were knocked out.
Arsenal are into the quarter-finals of the Europa League after beating Rennes 3-0 at the Emirates Stadium.
Pierre-Emerick Aubameyang scored twice and set-up Ainsley Maitland-Niles as the Gunners overturned a two-goal deficit from the first leg, progressing 4-3 overall.
They're joined in the last-eight by London rivals Chelsea, who thrashed Dynamo Kiev 5-0 away from home to complete an 8-0 aggregate victory.
Olivier Giroud claimed a hat-trick, with Marcus Alonso and Callum Hudson-Odoi also getting on the scoresheet.
Italian giants Internazionale were knocked out by Eintracht Frankfurt as Luka Jovic got the only goal of the tie for the German outfit at the San Siro.
That wasn't the only shock result however, as Spanish side Sevilla, who have won the competition a record five times, lost 4-3 to Slavia Prague after extra-time to go out 6-5 on aggregate.
Elsewhere, Villarreal beat Zenit St Petersburg 2-1 to complete a 5-2 aggregate win, Benfica overturned a 1-0 deficit from the first leg to beat Dinamo Zagreb 3-1 overall and Valencia secured a 1-1 draw at Krasnador to progress 3-2.
Formula One stewards handed Haas rookie driver Oliver Bearman a 10-place grid drop for his first home British Grand Prix for failing to comply with red warning flags in Saturday's final practice.
Seventh seed Mirra Andreeva outclassed American Hailey Baptiste 6-1 6-3 under the Court One roof to equal her best Wimbledon run by reaching the last 16 on Saturday.
Carrying a red floral wreath bearing his shirt number, Diogo Jota's Liverpool teammates joined relatives and residents in a small Portuguese town on Saturday for the funeral of the football star, who died with his brother in a car crash on Thursday.
An 83rd-minute Weverton own goal from a deflected Malo Gusto cross gave Chelsea a nervy 2-1 win over a spirited Palmeiras side in the Club World Cup quarter-finals on Friday.
Women's top seed Aryna Sabalenka fought off inspired home favourite Emma Raducanu in a cauldron-like Centre Court atmosphere to keep her Wimbledon quest on track but it was the end of the road for two other Grand Slam champions on Friday.