Syria's President Bashar al-Assad and his wife Asma have tested positive for COVID-19 after showing minor symptoms, his office said on Monday.
The pair are in good health and would keep working in isolation at home, the statement said.
Syria has seen a sharp rise in infections since mid-February. Health and aid officials say it remains difficult to gauge the full size of the outbreak given the lack of testing facilities in a fragile health system devastated by a decade of war.
Assad joins a growing list of world leaders who have tested positive for COVID-19, alongside Britain's Boris Johnson, France's Emmanuel Macron and former U.S. President Donald Trump.
Health workers said the authorities underplayed the size of the outbreak for most of last year, when official figures remained low as hospitals were overwhelmed and death notices appeared in newspapers.
The government denied undercounting the figures and has acknowledged in the last two months the country could be on the verge of a major spike.
It has urged people to wear face masks, take sanitary measures and avoid crowded areas.
Typhoon Kajiki brought torrential rains to Vietnam's north central coast on Monday, felling trees and flooding homes, despite wind speeds tapering off from earlier in the day.
Israeli strikes on Nasser Hospital in Gaza on Monday killed at least 15 people, including four journalists, one of whom worked for Reuters, Palestinian health officials said.
US National Guard troops patrolling the streets of Washington DC as part of what President Donald Trump said was his crackdown on crime will begin carrying weapons on Sunday night, two officials said.
Elon Musk's SpaceX on Sunday called off the launch of Starship's tenth mission from Texas over an issue at its launch site, delaying an attempt to achieve several long-sought development milestones missed due to past tests ending in early failures.
Israeli strikes hit the Yemeni capital Sanaa on Sunday in retaliation for Houthi missiles fired towards Israel, with a Houthi health official saying the attack killed six people and wounded 86.