Pakistan's foreign minister summoned the US ambassador after President Joe Biden said the country is "maybe one of the most dangerous nations in the world" as it has "nuclear weapons without any cohesion".
Biden made the remarks in a speech on Thursday.
Foreign Minister Bilawal Bhutto-Zardari said he was surprised by the comments. "As far as the question of the safety and security of Pakistan's nuclear assets are concerned, we meet all – each and every – international standard in accordance with the IAEA," he said at a press conference on Saturday.
The White House published a transcript of Biden's speech on its website.
Bhutto-Zardari said he didn't think the decision to summon the US ambassador would negatively affect relations with the United States and said officials could address any specific concerns Washington had on the nuclear programme.
Ties between Islamabad and Washington, once close allies, have just started to warm after some years of frosty relations, mostly due to concerns about Pakistan's alleged support of the Taliban in Afghanistan. Pakistan denies this support.
The foreign minister said worries about Pakistan's nuclear programme were not raised on his recent trip to Washington, where he held extensive meetings, including at the State Department.
Iran could be producing enriched uranium in a few months, the head of the UN nuclear watchdog Rafael Grossi was quoted as saying on Sunday, raising doubts about how effective US strikes to destroy Tehran's nuclear programme have been.
The Jerusalem District Court has cancelled this week's hearings in Prime Minister Benjamin Netanyahu's long-running corruption trial, accepting a request the Israeli leader made citing classified diplomatic and security grounds.
The Israeli military ordered Palestinians to evacuate areas in northern Gaza on Sunday before intensified fighting against Hamas, as US President Donald Trump called for an end to the war amid renewed efforts to broker a ceasefire.
Russia used hundreds of drones, cruise and ballistic missiles to attack western, southern and central Ukraine overnight, damaging homes and infrastructure and injuring at least six people, local authorities said on Sunday.
At least seven Palestinians were killed and several others injured early Sunday in a series of Israeli airstrikes targeting Gaza City and Khan Younis in the southern Gaza Strip, Palestinian News & Information Agency (WAFA) reported.