Nicaragua is breaking off diplomatic relations with Israel, the Central American nation said on Friday, calling the Israeli government "fascist" and "genocidal."
Nicaragua's government, in a statement, said the break in relations was due to Israel's attacks on Palestinian territories.
The nation's congress had, earlier in the day, passed a resolution requesting Nicaragua take action to coincide with the one-year anniversary of the Gaza war.
The conflict, the Nicaraguan government said, now also "extends against Lebanon and gravely threatens Syria, Yemen and Iran."
The Middle East is on high alert for further regional escalation after Iran launched a barrage of missiles at Israel on October 1.
Iran is also an ally of Nicaraguan President Daniel Ortega's administration. Nicaragua has become increasingly isolated in recent years after Ortega cracked down on anti-government protests in 2018, which rights groups say left around 300 dead.
US Defence Secretary Pete Hegseth said on Tuesday that the ceasefire with Iran was not over, even as the US and Iran exchanged fire in the Gulf as they wrestled for control of the Strait of Hormuz.
The US military said on Monday it destroyed six Iranian small boats and intercepted Iranian cruise missiles and drones as Tehran sought to thwart a new US naval effort to open shipping through the Strait of Hormuz.
A blast at a fireworks factory in China has killed at least 26 people and injured 61, flattening buildings and sending towering clouds of smoke into the sky, and prompting President Xi Jinping to order a thorough investigation, state media reported on Tuesday.
A Russian overnight missile and drone attack on Ukrainian gas production facilities killed five people, including two rescue workers, Ukrainian officials said on Tuesday, as Kyiv and Moscow exchanged rival ceasefire proposals.