Bahrain will suspend dine-in services at restaurants and cafes and move public and private schools to remote learning for three weeks to contain the spread of the coronavirus, the health ministry said.
It said it had detected a new variant of coronavirus in a number of cases, without specifying which kind.
The new lockdown measures will come into effect on Sunday.
There has been an uptick in coronavirus cases in the Gulf kingdom since December. The country registered 459 new cases on Wednesday, adding to a total of nearly 100,000 since the start of the pandemic, with 370 deaths.
The small island state has the third highest rate of vaccinations per capita in the world so far, according to the Our World in Data website, which is run by an Oxford University research programme.
Bahrain offers its citizens either the Pfizer/BioNTech vaccine or one manufactured by Chinese state-backed pharmaceutical giant Sinopharm free of charge.
The kingdom also approved the AstraZeneca COVID-19 vaccine on Monday for emergency use.
South Korea and the United States will cut short annual joint military drills to five days from 11 and scale back some field training, the allies said on Wednesday, after President Donald Trump ordered a substantial reduction in US participation.
An Israeli airstrike killed nine Palestinians at a police station in Gaza on Wednesday, medics said, two days after US envoy Jared Kushner ended a trip to the region that failed to push forward Donald Trump's plan to end the war in the enclave.
Thai schools conducted active shooter drills on Wednesday, as authorities moved to strengthen security measures two weeks after a 14-year-old opened fire at a school and killed at least eight people.
At least 21 people have died and four others injured in a head-on collision between a bus and a truck in the BR-373 highway in Brazil's southern state of Parana, the road operator said on Wednesday in an X post.