TikTok will exit the Hong Kong market after the region adopted a new national security law granting expanded powers to the Chinese government.
Tech giant ByteDance, which is based in Beijing and owns the app, has become the first internet company to withdraw from Hong Kong.
"In light of recent events, we've decided to stop operations of the TikTok app in Hong Kong," a TikTok spokesman told Reuters.
The popular short video app had previously said it wouldn't comply with any requests made by the Chinese government to censor content or share user data.
It comes after tech giants Facebook, WhatsApp and Twitter announced that they will stop processing law enforcement requests for user data in the city.