Barcelona are two points clear at the top of the La Liga table after crushing Real Valladolid 5-1.
Lionel Messi scored twice and grabbed two assists to set up the win for the defending champions.
Meanwhile, Atletico Madrid have slipped to third following their 1-1 draw with Deportivo Alaves.
In Italy's Serie A, Inter Milan are back at the top of the standings after beating Brescia 2-1.
However, Juventus can reclaim the number one spot if they beat Genoa on Wednesday.
Everton deal Liverpool big blow with shock 2-0 derby victory
Everton's Jarrad Branthwaite and Dominic Calvert-Lewin scored in a pulsating 2-0 home victory over Liverpool in the Merseyside derby on Wednesday that could prove to be the death of the visitors' withering Premier League title hopes.
Xavi to continue as Barcelona manager, LaLiga club confirms
Barcelona boss Xavi Hernandez on Wednesday reversed his decision to step down at the end of the season and agreed to stay in charge of the LaLiga giants for the 2024-25 campaign, a club spokesperson said.
Fernandes digs Man Utd out of hole in win over Sheff Utd
Manchester United captain Bruno Fernandes came to his side's rescue with two goals in a 4-2 home victory over the Premier League's bottom club Sheffield United on Wednesday just when more trouble loomed for beleaguered manager Erik ten Hag.
Nadal uncertain over Roland Garros appearance
Spain's Rafael Nadal said on Wednesday that he is not sure if he will be able to play at next month's French Open after pushing through the pain barrier in his comeback from injury.
Arsenal hammer Chelsea to move three points clear at top
Ruthless Arsenal threw down the gauntlet in the Premier League title race with a 5-0 thrashing of London rivals Chelsea to roar three points clear at the top of the table on Tuesday.
