According to manager Ole Gunnar Solskjaer, the France midfielder needs an operation on his ankle.
The 26-year-old only made his comeback last month, as his ankle problem kept him out since late September last year.
Scott McTominay is currently also out injured.
Pogba has played only eight times this season after having surgery to correct another ankle injury.
Runners can set world records at Dubai Marathon under new partnership
Dubai Marathon has partnered with Guinness World Records (GWR) to give runners a chance to set official global records during the upcoming race on February 1.
Australia captain Healy to retire after upcoming India series
Alyssa Healy, a mainstay of Australia's dominant women's cricket team for 15 years and latterly its captain, has announced that she will retire from the game after the upcoming multi-format series against India.
Real Madrid parts ways with coach Xabi Alonso
Real Madrid has announced on Monday that Xabi Alonso has left his role as head coach "by mutual consent," with Alvaro Arbeloa promoted from the club's reserve team Castilla coach to replace him.
Liverpool defeats Barnsley after Szoboszlai mistake
Dominik Szoboszlai has scored a stunner and gave away a howler as Liverpool beat third-tier Barnsley 4-1 on Monday to set up a home FA Cup fourth round clash with Premier League rivals Brighton & Hove Albion.
CAF to investigate post-match violence at Africa Cup of Nations
Violent confrontations at the conclusion of two of the Africa Cup of Nations quarter-finals at the weekend are to be investigated with possible sanctions to be imposed, the Confederation of African Football (CAF) said.
