England beat Ireland and France by 12 and 36 points respectively in their first two matches of the campaign.
They are currently ranked third in the world.
Play from the Millennium Stadium in Cardiff gets underway at 8:45 PM UAE time.
Meanwhile Scotland travel to France for their latest Six Nations fixture.
Action from the Stade de France starts at 6:15 PM UAE time.
India beat England in thriller to reach T20 World Cup final
Jacob Bethell's thrilling century was not enough as India pipped England by just seven runs to seal a spot in the T20 World Cup final in a high-scoring thriller in Mumbai.
EFL Championship playoffs expanded to six teams
The EFL Championship promotion playoffs will expand from four teams to six starting in the 2026-27 season, the English Football League said on Thursday, in a bid to increase the number of competitive games in the season's closing stages.
Aston Martin to limit laps in Australia with drivers at risk of nerve damage
Aston Martin will limit their laps at the season-opening Australian Grand Prix to avoid the risk of their drivers suffering nerve damage from vibrations coming through the steering wheel, team principal Adrian Newey said on Thursday.
Ten-man Newcastle beat Man United; Arsenal go 7 points clear
William Osula came off the bench to score a late winner as a 10-man Newcastle United beat high-flying Manchester United 2-1 in the Premier League on Wednesday to end Michael Carrick's unbeaten run as interim manager.
South Korea on brink of quarter-finals after 3-0 win over Philippines
Park Soo-jeong has scored the pick of the goals as South Korea all but secured passage to the quarter-finals of the Women's Asian Cup with a 3-0 win over the Philippines at Gold Coast Stadium on Thursday.
