Novak Djokovic will miss next week's Miami Open after the Serbian was denied an exemption that would have allowed him to enter the U.S. despite not being vaccinated against COVID-19.
"We tried to get Novak Djokovic to be allowed to get an exemption, but that wasn't able to happen," tournament director James Blake told Tennis Channel.
"Obviously, we're one of the premier tournaments in the world, we'd like to have the best players that can play. We did all that we could. We tried to talk to the government, but that's out of our hands."
Florida Governor Ron DeSantis and the state's two U.S. senators were among those calling on the Biden administration to allow world number one Djokovic to enter the U.S. and compete at the tournament he has won six times.
The 35-year-old is also missing the ongoing Masters event in Indian Wells, California due to inability to secure the exemption.
The U.S. currently bars unvaccinated foreigners from entry into the country, a policy that is expected to be lifted when the government ends its COVID-19 emergency declarations on May 11.
Djokovic, who missed last year's Australian Open after being deported from that country due to his vaccination status, has said he would skip Grand Slams rather than have a COVID shot.
He won his record-tying 22nd Grand Slam at the Australian Open in January. He has not played at Indian Wells or the Miami Open - which together comprise the "Sunshine Double" - since 2019.