The World Health Organisation has said it has lost communication with its contacts in Al Shifa hospital in northern Gaza.
In a statement it expressed its deep concern about the safety of health workers and hundreds of sick and injured people, including children in nurseries and displaced persons, who remain inside.
The hospital is the largest medical complex in Gaza.
According to the latest reports, the number of in-patients is almost double the hospital's capacity, although services are limited to emergency care needed to save lives.
The organisation reiterated its call for an immediate ceasefire in Gaza "as the only way to save lives and put an end to the horrific suffering there".


US to blockade Iran on Monday after talks fail to yield a deal
Haiti declares three days of national mourning for 25 killed in stampede
Australia appoints woman to lead its army for the first time
Orban ousted after 16 years as Hungarians flock to pro-EU rival
Trump vows to blockade Strait of Hormuz after Iran peace talks stumble
