A World Health Organisation (WHO) official said on Tuesday that the first five patients were transferred through Gaza's Rafah crossing with Egypt, which reopened on Monday.
"On the second of February, WHO and partners supported the medical evacuation of five patients and seven companions to Egypt via the Rafah crossing," said WHO spokesperson Christian Lindmeier.
"It was the first medical evacuation through this route since sometime in 2025," he said referring to a limited number of evacuations during an early 2025 ceasefire.
Over 18,500 patients are awaiting evacuations after the two-year war, he said, with trauma injuries from the war as well as chronic conditions such as cancer and diabetes.
A UNICEF spokesperson said that more than 3,000 of them were children. Gaza health authorities are choosing whom to prioritise among the sick and wounded, Lindmeier said.
"We know that patients have died basically waiting for evacuation, and that's something which is horrible when you know just a few miles or kilometers outside that border, help is available," he added.
A US fighter jet has been shot down over Iran and a search-and-rescue operation is underway for any survivors, two US officials told Reuters on Friday, in the first such known incident since the war began nearly five weeks ago.
A large-scale daytime Russian strike killed at least two people in Ukraine on Friday, officials said, in what President Volodymyr Zelenskyy denounced as an "Easter escalation", as Moscow shifts tactics to avoid Ukrainian air defences.
Kuwait's Ministry of Electricity, Water, and Renewable Energy has reported material damage to a power and water desalination plant due to an Iranian attack on Friday.
US President Donald Trump has warned late on Thursday about striking and destroying bridges and electric power plants in Iran in his latest threat to hit the country's infrastructure.
The Kuwaiti Petroleum Corporation (KPC) has reported a drone attack that targeted its Mina al-Ahmadi refinery early on Friday, which resulted in a fire breaking out at its operating units, with no injuries reported.