NASA's next-generation Mars rover Perseverance blasted off from Florida's Cape Canaveral on Thursday atop an Atlas 5 rocket on a $2.4 billion mission to search for traces of potential past life.
Perseverance is due to land at the base of an 820-foot-deep crater called Jezero, a former lake from 3.5 billion years ago that scientists suspect could bear evidence of potential past microbial life on Mars.
It is expected to reach Mars next February.
Scientists have long debated whether Mars - once a much more hospitable place than it is today - ever harbored life. Water is considered a key ingredient for life, and the Mars billions of years ago had lots of it on the surface before the planet became a harsh and desolate outpost.
The next-generation robotic rover - a car-sized six-wheeled scientific vehicle - is also scheduled to deploy a mini helicopter on Mars and test out equipment for future human missions to the fourth planet from the sun.
This marked NASA's ninth journey to the Martian surface.
This was scheduled as the third launch from Earth to Mars during a busy month of July, following probes sent by the United Arab Emirates and China.
US Secretary of State Marco Rubio said on Thursday that the United States remains prepared to play a "constructive role" in helping bring an end to the war in Ukraine, following talks with Russian Foreign Minister Sergei Lavrov on the sidelines of an ASEAN gathering in Manila.
Indian Prime Minister Narendra Modi said on Thursday that "fast-track" courts would be set up to prosecute those behind exam paper leaks, his first public response after days of youth protests demanding the resignation of the education minister.
Two earthquakes that rocked Venezuela on June 24 caused $19.6 billion in direct physical damage, but the cost of rebuilding could be twice that much or more, the World Bank said in an early assessment released on Thursday.
Ousted Ukrainian defence minister Mykhailo Fedorov said on Thursday he would accept no other government position besides his former job, escalating a political crisis that has gripped Ukraine at a pivotal point in the war with Russia.