Iran's consulate in the Syrian capital Damascus was flattened on Monday in what Syrian and Iranian media described as an Israeli air strike.
A Lebanese security source, speaking to Reuters, said one of the dead was Mohammad Reza Zahedi, a senior commander in Iran's Revolutionary Guards Corps (IRGC). Iranian state television said several Iranian diplomats had been killed.
Israel, which has repeatedly hit Iranian targets during the six-month war in Gaza, declined to comment on the incident, following its usual practice.
An Israeli military spokesperson said: "We do not comment on reports in the foreign media."
Iran's Tasnim news agency said five people were killed in the Israeli strike. Syria's SANA state news agency reported an unspecified number of deaths and injuries.
Since the Palestinian group Hamas' attack on Israel on October 7, Israel has ramped up airstrikes in Syria against Lebanon's Hezbollah militia and Iran's Guards, both of which support the government of President Bashar Al Assad.
A state of relative calm prevailed around the Strait of Hormuz on Saturday, after days of sporadic flare-ups, as the United States waited for Iran's response to its latest proposals to end more than two months of fighting and begin peace talks.
A car bombing at a police post killed at least three officers in northwestern Pakistan on Saturday and was followed by an ambush on police personnel rushing to the scene to provide backup, security officials said.
An Israeli strike on the southern Lebanese town of Saksakiyeh killed at least seven people, including a child, and wounded 15 on Saturday, Lebanon's health ministry said.
Countries prepared to evacuate their citizens from the luxury cruise ship hit by a deadly strain of hantavirus that is due to anchor near Tenerife early on Sunday, as health authorities said the risk of the virus spreading was low.
Centre-right leader Peter Magyar was sworn in as Hungary's prime minister on Saturday, propelled into office on promises of change after years of economic stagnation and strained ties with key allies under his predecessor Viktor Orban.